Suzanne T. Ildstad, M.D.
Intro | Research Interests | Biosketch | Selected Publications | Staff | Protocols |

Rezzoug F, Huang Y, Tanner MK, Wysoczynski M, Schanie CL, Chilton PM, Ratajczak MZ, Fugier-Vivier IJ, Ildstad ST.

TNF-alpha is critical to facilitate hemopoietic stem cell engraftment and function.

J Immunol. 2008 Jan 1;180(1):49-57.

PMID: 18097003

Adamson LA, Huang WC, Breidenbach WC, Rahhal D, Xu H, Huang Y, Pidwell DJ, Wei FC, Tobin G, Ildstad ST.

A modified model of hindlimb osteomyocutaneous flap for the study of tolerance to composite tissue allografts.

Microsurgery. 2007;27(7):630-6.

http://www.ncbi.nlm.nih.gov/sites/entrez/17868137

Xu H, Yan J, Huang Y, Chilton PM, Ding C, Schanie CL, Wang L, Ildstad ST.

Co-stimulatory blockade of CD154:CD40 in combination with T-cell lymphodepletion results in prevention of allogeneic sensitization.

Blood. 2007 Sep 7;

http://www.ncbi.nlm.nih.gov/sites/entrez/17827394

Li Y, Atmaca-Sonmez P, Schanie CL, Ildstad ST, Kaplan HJ, Enzmann V.

Endogenous bone marrow derived cells express retinal pigment epithelium cell markers and migrate to focal areas of RPE damage.

Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4321-7.

http://www.ncbi.nlm.nih.gov/sites/entrez/17724223

Xu H, Chilton PM, Huang Y, Schanie CL, Yan J, Ildstad ST.

Addition of cyclophosphamide to T-cell depletion-based nonmyeloablative conditioning allows donor T-cell engraftment and clonal deletion of alloreactive host T-cells after bone marrow transplantation.

Transplantation. 2007 Apr 15;83(7):954-63.

http://www.ncbi.nlm.nih.gov/sites/entrez/17460568

Tobin GR, Breidenbach WC 3rd, Pidwell DJ, Ildstad ST, Ravindra KV.

Transplantation of the hand, face, and composite structures: evolution and current status.

Clin Plast Surg. 2007 Apr;34(2):271-8, ix-x. Review.

http://www.ncbi.nlm.nih.gov/sites/entrez/17418676

Facilitating cells: novel promoters of stem cell alloengraftment and donor-specific transplantation tolerance in the absence of GVHD.

Crit Rev Oncol Hematol. 2007 Jan;61(1):26-43. Epub 2006 Dec 5. Review.

http://www.ncbi.nlm.nih.gov/sites/entrez/17150368

Atmaca-Sonmez P, Li Y, Yamauchi Y, Schanie CL, Ildstad ST, Kaplan HJ, Enzmann V.  Systemically transferred hematopoietic stem cells home to the subretinal space and express RPE-65 in a mouse model of retinal pigment epithelium damage.

Exp Eye Res. 2006 Nov;83(5):1295-302. Epub 2006 Sep 1.

http://www.ncbi.nlm.nih.gov/sites/entrez/16949576

Xu H, Chilton PM, Tanner MK, Huang Y, Schanie CL, Dy-Liacco M, Yan J, Ildstad ST.

Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients.

Blood. 2006 Nov 15;108(10):3611-9. Epub 2006 Aug 3.

http://www.ncbi.nlm.nih.gov/sites/entrez/16888094

Huang Y, Kucia M, Rezzoug F, Ratajczak J, Tanner MK, Ratajczak MZ, Schanie CL, Xu H, Fugier-Vivier I, Ildstad ST.

Flt3-ligand-mobilized peripheral blood, but not Flt3-ligand-expanded bone marrow, facilitating cells promote establishment of chimerism and tolerance.

Stem Cells. 2006 Apr;24(4):936-48.

http://www.ncbi.nlm.nih.gov/sites/entrez/16644924

Li Y, Reca RG, Atmaca-Sonmez P, Ratajczak MZ, Ildstad ST, Kaplan HJ, Enzmann V.

Retinal pigment epithelium damage enhances expression of chemoattractants and migration of bone marrow-derived stem cells.

Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1646-52.

http://www.ncbi.nlm.nih.gov/sites/entrez/16565405

Dawn B, Guo Y, Rezazadeh A, Huang Y, Stein AB, Hunt G, Tiwari S, Varma J, Gu Y, Prabhu SD, Kajstura J, Anversa P, Ildstad ST, Bolli R.

Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function.

Circ Res. 2006 Apr 28;98(8):1098-105. Epub 2006 Mar 23.

http://www.ncbi.nlm.nih.gov/sites/entrez/16556872

Kucia M, Zhang YP, Reca R, Wysoczynski M, Machalinski B, Majka M, Ildstad ST, Ratajczak J, Shields CB, Ratajczak MZ.

Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following stroke.

Leukemia. 2006 Jan;20(1):18-28.

http://www.ncbi.nlm.nih.gov/sites/entrez/16270036

Huang Y, Rezzoug F, Xu H, Chilton PM, Schanie CL, Fugier-Vivier I, Ildstad ST.

NK cells play a critical role in the regulation of class I-deficient hemopoietic stem cell engraftment: evidence for NK tolerance correlates with receptor editing.

J Immunol. 2005 Sep 15;175(6):3753-61.

http://www.ncbi.nlm.nih.gov/sites/entrez/16148121

Fugier-Vivier IJ, Rezzoug F, Huang Y, Graul-Layman AJ, Schanie CL, Xu H, Chilton PM, Ildstad ST.

Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment.

J Exp Med. 2005 Feb 7;201(3):373-83.

http://www.ncbi.nlm.nih.gov/sites/entrez/15699072

Michaels MG, Kaufman C, Volberding PA, Gupta P, Switzer WM, Heneine W, Sandstrom P, Kaplan L, Swift P, Damon L, Ildstad ST.

Baboon bone-marrow xenotransplant in a patient with advanced HIV disease: case report and 8-year follow-up.

Transplantation. 2004 Dec 15;78(11):1582-9.

http://www.ncbi.nlm.nih.gov/sites/entrez/15591945

Kucia M, Dawn B, Hunt G, Guo Y, Wysoczynski M, Majka M, Ratajczak J, Rezzoug F, Ildstad ST, Bolli R, Ratajczak MZ.

Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction.

Circ Res. 2004 Dec 10;95(12):1191-9. Epub 2004 Nov 18.

http://www.ncbi.nlm.nih.gov/sites/entrez/15550692

Xu H, Exner BG, Chilton PM, Schanie C, Ildstad ST.

CD45 congenic bone marrow transplantation: evidence for T cell-mediated immunity.

Stem Cells. 2004;22(6):1039-48.

http://www.ncbi.nlm.nih.gov/sites/entrez/15536194

Chilton PM, Rezzoug F, Ratajczak MZ, Fugier-Vivier I, Ratajczak J, Kucia M, Huang Y, Tanner MK, Ildstad ST.

Hematopoietic stem cells from NOD mice exhibit autonomous behavior and a competitive advantage in allogeneic recipients.

Blood. 2005 Mar 1;105(5):2189-97.

http://www.ncbi.nlm.nih.gov/sites/entrez/15522953

Science from Bench to Bedside