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Aplastic Anemia

More About Aplastic Anemia

Aplastic Anemia is classified as a bone marrow disorder caused by the deficiency of the production of red blood cells. The cause of aplastic anemia is usually not known, but a small number of cases may be caused by exposure to chemical and antineoplastic agents and ionizing radiation. Aplastic anemia most commonly affects adolescents and young adults. Infiltration of cells into the bone marrow that are not normally present in bone marrow can interfere with normal blood production. Aplastic anemia may be acute or chronic, but it will always progress.

Patients with aplastic anemia learn to take steps to prevent infections and to get adequate rest. When the platelet count becomes too low (<20,000/mm3), steps are taken to prevent bleeding: not shaving with a razor, humidifying to prevent dry mucous membranes and using stool softeners and a healthy diet to promote regular bowel movements. Patients can check for bleeding early by checking for blood in urine and stools using a chemical test and by examining the skin for petechiae and ecchymoses. A diet high in vitamins and proteins is recommended.

Individuals with aplastic anemia may be treated with either bone marrow transplantation or immunosuppressive agents.

Symptoms: fatigue, rash, pallor, shortness of breath, rapid heart rate, irregular heart beat, easy bruising, nose bleeds, bleeding gums, prolonged bleeding, and lymph nodes may be enlarged (rare).

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